Androgenetic alopecia (male pattern hair loss) is the most common type of hair loss in men. The condition is characterized by the progressive loss of terminal hairs on the scalp in a characteristic distribution. The anterior scalp, mid scalp, temporal scalp, and vertex of the scalp are typical sites of involvement.
Androgenetic alopecia is considered an androgen-dependent trait that requires a genetic predisposition. The interaction of these factors and other mechanisms that remain to be elucidated contributes to follicular miniaturization (the transition of larger, terminal hair fibers to small vellus hair fibers) in susceptible scalp areas.
Dihydrotestosterone (DHT) is the key androgen involved in the induction and promotion of male androgenetic alopecia. DHT is a potent metabolite of testosterone and, compared with testosterone, has greater affinity for the androgen receptor.
The 5-alpha-reductase enzyme inhibitors, finasteride and dutasteride, mediate the conversion of testosterone to DHT and are main stay therapy for androgenetic alopecia.
What are Dr. Reszko’s favorite hair rejuvenation the treatment options?
Platelet-rich plasma (PRP) therapy is an increasingly popular hair regrowth solution. PRP, refers to a portion of whole blood i.e. platelets, that is separated from the blood through the process of centrifugation.
First, blood is withdrawn just like during routine blood testing. Then the platelets are concentrated and separated. Once separated, the concentrated platelets are injected into the skin, and also applied topically during and after associated microneedling. Similar to one’s own stem cells, the platelets can help infuse nutrients into the skin and hair, boosting its natural healing properties.
PRP treatments are used to stimulate the stem cells and inactive scalp hair follicles and help to activate hair regeneration and growth, for thicker, fuller hair.
PRP for Hair Re-Growth
Platelets have been found to contain a number of growth factors and cytokines including:
The end benefit of the combination of these growth factors is increased the vascularity to the treated area, decreasing the inflammation, healing and re-generation of tissue and clinically visible hair regrowth.
Length of Procedure/Maintenance Treatments
A single PRP session takes about 60 minutes. A course of treatments, will be determined by the extent of your hair loss and final goals; however between 3 to 5 sessions, about 4 weeks apart are recommended. Additional maintenance treatments may be scheduled a 3 to 4 times per year.
Avoid makeup and sunscreen for 24 hours after the procedure. Redness or inflammation may be common for a few days, post treatment, at the application site, but quickly resolves.
The benefits of PRP It will vary from person to person. Most people have results lasting over a year, and the process can be repeated.